Fatigue lowers the Critical Hit Rate of a Champion, making it a good counter against Champions that need Critical Hits like Iron Fist.
Ant-Man
Light Attacks :
20% chance to Fatigue the opponent for 15 seconds, lowering their Critical Rating by -113.16 - -84.21
RarityRankValue
2*1-84.21
3*4-97.37
4*5-105.26
5*5-110.53
6*3-113.16
.
Captain America
Blocking :
A Perfect Block has a 90% chance to Fatigue the opponent, lowering their Critical Rating by -238.89 - -177.78
RarityRankValue
2*1-177.78
3*4-205.56
4*5-222.22
5*5-233.33
6*3-238.89
for 12 seconds.
Colossus
Special Attack 3 :
100% chance to inflict an indefinite Passive Fatigue on the opponent, reducing their Critical Rating by -2150 - -1550
RarityRankValue
1*1-1550
2*1-1600
3*4-1850
4*5-2000
5*5-2100
6*3-2150
.
Psycho-Man
Opponent activates a Special Attack:
Psycho-Man’s mechanical exoskeleton causes his Opponents to suffer -X Critical Rating during their Special Attacks.
Joe Fixit
Passive :
HEARTS: Joe triggers his accelerated healing ability, granting 84.21 - 113.16
RarityRankValue
2*184.21
3*497.37
4*5105.26
5*5110.53
6*3113.16
health recovery per minute.
SPADES: Mr. Fixit is morally ambiguous at best and knows how to make his punches hurt. Each attack has a 14% chance to Weaken or Fatigue the opponent, reducing attack by 10% and Critical Rating by 84.21 - 113.16
RarityRankValue
2*184.21
3*497.37
4*5105.26
5*5110.53
6*3113.16
.
CLUBS: Joe isn’t some dumb brute and he’s smart enough to take advantage of anyone who thinks he is, granting X Critical Rating for each hit of his combo meter.
DIAMONDS: He may not be as big as the Hulk, but you still won’t like him when he’s angry. Joe gains up to X Attack based on lost health.
Spider-Man (Miles Morales)
Special Attack 2 :
Miles’ unpredictable Venom Blast has varying effects based on Champion Class. The chance to activate a Venom blast is increased by up to 12% the smaller the target is.
Science & Cosmic Champions: 65% chance to Stun the opponent for 2.5 seconds.
Tech & Skill Champions: 60% chance to Power Drain the opponent, removing 28% of the opponent’s Max Power.
Mystic & Mutant Champions: 70% Chance to Fatigue the opponent, reducing Critical Rating by X for 7 seconds.
Void
Intimidating Presence:
For each Champion alive on the opponent’s team, Intimidating Presence Debuffs have a 0.6 second delay before fully activating.
Agility Debuff - Reduces Ability Accuracy of Evade and the Dexterity Mastery by 30%. Max Stacks: 2
Fatigue Debuff - Reduces Critical Rating by X. Max Stacks: 2
Petrify Debuff - Reduces the effectiveness of Power Gain and Regeneration by 50%. Max Stacks: 2
When all Intimidating Presence Debuffs are at max stacks, those Debuffs will be removed after 5 seconds.

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